Probióticos e o Covid-19 (2020)

Autores: Benedetta Bottari, Vincenzo Castellone, Erasmo Neviani. Desde que foi decretada pela OMS em março de 2020, a pandemia causada pelo vírus SARS-CoV-2 foi se alastrando de maneira cada vez mais rápida e passando por diversos tipos de mutações. Um estudo (Bottari et al., 2020) analisou o efeito terapêutico de probióticos para alívio dos sintomas […]
Vitamina K2 garante prevenção e tratamento para o Alzheimer (2021)

Revista: Nutrients. Autores: Alexander Popescu, Monica German O Alzheimer é uma das doenças que mais acomete idosos ao redor do mundo, tendo diversos fatores que podem desencadear o seu desenvolvimento, como o estilo de vida levado, a alimentação pobre em nutrientes e o sedentarismo. Um estudo (2021) analisou o efeito da suplementação da vitamina K2 […]
Melatonina-índice como biomarcador para prever a distribuição de portadores de sars-cov-2 pré-sintomáticos e assintomáticos

ABSTRACT The pandemic dissemination of the SARS-CoV-2 led, on the one hand, to a worldwide effort to develop mechanistic-based therapeutics and vaccines, and on the other hand, the searching for determining the spreaders and the mechanisms of transmission. Melatonin, a multitask molecule, orchestrates defense responses by allowing the proper mounting, duration, and magnitude of innate […]
A exposição química do envelhecimento humano (2020)

Aging is an inevitable biological phenomenon displayed by single cells and organs to entire organismal systems. Aging as a biological process is characterized as a progressive decline in intrinsic biological function. Understanding the causative mechanisms of aging has always captured the imagination of researchers since time immemorial. Although both biological and chronological aging are well […]
Uma visão multimônica do complexo mecanismo de calcificação vascular (2021)

Vascular calcification is a high incidence and high risk disease with increasing morbidity and high mortality, which is considered the consequence of smooth muscle cell transdifferentiation initiating the mechanism of accumulation of hydroxyl calcium phosphate. Vascular calcification is also thought to be strongly associated with poor outcomes in diabetes and chronic kidney disease. Numerous studies […]
A relevância da medicina complementar e integrativa na pandemia do covid-19: uma revisão qualitativa da literatura (2020)

Background: During the COVID-19 pandemic people are facing risks of adverse health effects due to the restrictions implemented such as quarantine measures, reduced social contact, and self-isolation. In this qualitative review, we collected data on potential preventive and therapeutic health benefits of Complementary and Integrative Medicine (CIM) that might be useful during the COVID-19 pandemic. […]
Disfunção mitocondrial na doença hepática gordurosa não alcoólica e doença hepática relacionada ao álcool (2021)

Abstract: Fatty liver disease constitutes a spectrum of liver diseases which begin with simple steatosis and may progress to advance stages of steatohepatitis, cirrhosis, and hepatocellular carcinoma (HCC). The two main etiologies are alcohol related fatty liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD). NAFLD is a global health epidemic strongly associated with modern […]
Câncer de mama: uma abordagem de medicina de estilo de vida (2020)

Abstract: Breast cancer is the most common female cancer diagnosis in the United States (excluding skin cancers), and the second leading cause of female cancer death. This article highlights the role that lifestyle plays in primary breast cancer prevention, breast cancer treatment, and tertiary breast cancer prevention. Current data regarding the benefits of a predominantly […]
O interactoma microbiano-hospedeiro oral: um cronômetro ecológico da saúde? (2020)

Introduction The oral cavity is of major importance for human health and well-being. Not only does it provide entry to the digestive and respiratory systems, but it also provides immunity, and a protective barrier from invading pathogens (Box 1). Approximately 700 oral bacterial species have been identified to date, with evidence of 296 species-level taxa […]
Interações de exposição a drogas: a próxima fronteira na medicina de precisão (2020)

Drug–drug interactions are a known concern during medical treatment. However, in addition to therapeutic drugs, humans are exposed to thousands of environment-and food-related chemicals on a daily basis. The exposome (i.e., the total measure of environmental factors on the human body) is an emerging concept in the field of environmental health. Many chemicals have the […]