Abstract
Development of central nervous system (CNS) is regulated by both intrinsic and peripheral signals. Previous studies
have suggested that environmental factors affect neurological activities under both physiological and pathological
conditions. Although there is anatomical separation, emerging evidence has indicated the existence of bidirectional
interaction between gut microbiota, i.e., (diverse microorganisms colonizing human intestine), and brain. The
cross-talk between gut microbiota and brain may have crucial impact during basic neurogenerative processes,
in neurodegenerative disorders and tumors of CNS. In this review, we discuss the biological interplay between
gut-brain axis, and further explore how this communication may be dysregulated in neurological diseases. Further, we
highlight new insights in modification of gut microbiota composition, which may emerge as a promising therapeutic
approach to treat CNS disorders.

Download: 2019_Impact of microbiota on central nervous system and neurological diseases

Deixe um comentário

O seu endereço de e-mail não será publicado. Campos obrigatórios são marcados com *

Nosso site utiliza cookies que são úteis para ver como você interage com as páginas e os elementos do site. Com isto, podemos aprimorar nosso conteúdo e deixa-lo sempre mais atraente e interessante. Ao aceitar, você concorda com o uso de cookies. Política de Privacidade